Requirement of bic/microRNA-155 for Normal Immune Function

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Requirement of bic/microRNA-155 for normal immune function.

MicroRNAs are a class of small RNAs that are increasingly being recognized as important regulators of gene expression. Although hundreds of microRNAs are present in the mammalian genome, genetic studies addressing their physiological roles are at an early stage. We have shown that mice deficient for bic/microRNA-155 are immunodeficient and display increased lung airway remodeling. We demonstrat...

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ژورنال

عنوان ژورنال: Science

سال: 2007

ISSN: 0036-8075,1095-9203

DOI: 10.1126/science.1139253